相关实验视频

Updated: Jul 27, 2026

In vitro Assembly of Semi-artificial Molecular Machine and its Use for Detection of DNA Damage
08:56

In vitro Assembly of Semi-artificial Molecular Machine and its Use for Detection of DNA Damage

Published on: January 11, 2012

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内核酶IV和T4结合酶增强了低丰度突变的检测

Bo Li1, Chunyan Wang1

  • 1Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot, 010020, China. chywang@imu.edu.cn.

The Analyst
|January 17, 2024
PubMed
概括

这项研究引入了一种新型突变检测方法,使用IV内核酶和DNA结合酶与定量PCR (qPCR). 这种方法有效地检测出低丰度的DNA突变,显示出早期癌症诊断的前景.

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Proofreading and DNA Repair Assay Using Single Nucleotide Extension and MALDI-TOF Mass Spectrometry Analysis11:08

Proofreading and DNA Repair Assay Using Single Nucleotide Extension and MALDI-TOF Mass Spectrometry Analysis

Published on: June 19, 2018

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Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication05:33

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

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相关概念视频

Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...