胃癌治疗方案的临床管理
Juliette Boilève1, Yann Touchefeu1, Tamara Matysiak-Budnik2
1Institut Des Maladies de L'Appareil Digestif (IMAD), Nantes Université, CHU Nantes, Hépato-Gastroentérologie, Inserm CIC 1413, 44000, Nantes, France.
胃癌治疗的进展包括早期的内镜切除和晚期疾病的手术. 新的向疗法和免疫疗法正在改善转移性胃癌的结果.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 分子生物学分子生物学
背景情况:
- 胃癌是全球癌症死亡的主要原因之一.
- 治疗方法从早期的内镜切除到局部晚期疾病的手术各不相同.
研究的目的:
- 为了总结胃癌的当前治疗策略.
- 为了突出管理晚期和转移性胃癌的最新进展.
主要方法:
- 对胃癌的既定和新兴治疗方法的审查.
- 专注于手术,化疗,向和免疫治疗方法.
主要成果:
- 早期的胃癌容易接受内镜切除.
- 用D2淋巴切除术为切除瘤的手术.
- 化疗,向性疗法 (特拉斯图苏马布,拉穆齐鲁马布,佐尔贝图西马布) 和免疫疗法 (对于MSI或PD-L1阳性) 是疾病晚期的关键.
结论:
- 胃癌治疗的重大进展是由理解分子异质性推动的.
- 个性化治疗方法正在出现.
- 未来的管理可能会随着新的目标和疗法而演变.
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