高血压发病年龄和老年人的认知功能:来自NHANES 2011-2014年的观察性研究
1Department of Gastroenterology and Hepatology, The Sixth People's Hospital of Chengdu, Chengdu, China.
European geriatric medicine
|January 17, 2024
概括
早期高血压发病 (在35岁之前) 与认知功能恶化和老年人认知能力下降的可能性更高有关. 这凸显了从小就管理高血压对大脑健康的重要性.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 心血管医学 心血管医学
背景情况:
- 高血压是老年人中普遍存在的疾病.
- 高血压发病的年龄可能会影响其对健康的长期影响.
- 认知能力下降是老年人群的一个重大问题.
研究的目的:
- 调查高血压发病年龄与认知功能之间的关联.
- 为了评估美国老年人的认知表现,高血压发病年龄不同.
主要方法:
- 来自国家健康和营养检查调查 (2011-2014) 的2334名老年人的分析.
- 高血压发病年龄由临床诊断或医生通知来定义.
- 使用数字符号替换测试 (DSST),动物流利性测试,CERAD和复合z-score评估的认知功能.
主要成果:
- 早期出现的高血压 (年龄<35岁) 与大多数认知测试中的表现最差有关.
- 与正常血压患者相比,早期高血压患者与DSST和复合z-score有显著的负面关联.
- 早期出现的高血压增加了认知能力下降的几率,根据DSST和复合z-score的定义.
结论:
- 在35岁之前出现的高血压与老年人的认知功能下降密切相关.
- 早期出现的高血压是老年人认知能力下降的危险因素.
- 从年轻时开始管理高血压可能对在晚年保持认知健康至关重要.
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