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长期COVID患者中的焦虑和抑郁症状:回顾性队列研究
Michael C Sauer1, Patrick B Barlow2,3, Alejandro P Comellas3,4
1Department of Internal Medicine, University of Iowa Division of General Internal Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA, 52242, USA. mcsr@uiowa.edu.
European archives of psychiatry and clinical neuroscience
|January 17, 2024
概括
后急性COVID-19 (PASC) 患者表现出更高的焦虑和抑郁负担,特别是那些没有先前病史的人. 这些心理健康影响在PASC个体中可能更明显.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- COVID-19 (PASC) 后急性后果是一个日益增长的挑战,具有重大的心理健康影响.
- 焦虑和抑郁是一般人群中常见的并发症,但它们在PASC患者中的患病率需要进一步调查.
研究的目的:
- 评估参加COVID-19后诊所的患者焦虑和抑郁的负担.
- 分析患者因素,特别是先前的心理健康状况史,如何影响PASC患者的焦虑和抑郁症得分.
主要方法:
- 追溯队列研究比较PASC患者 (N=455) 来自COVID后诊所与一般内科 (GIM) 患者 (N=94).
- 利用了通用焦虑障碍-7 (GAD-7) 和患者健康问卷-9 (PHQ-9) 的评分进行评估.
- 基于电子医疗记录中焦虑和抑郁症的存在或不存在的比较得分.
主要成果:
- 没有先前抑郁病史的PASC患者在GAD-7和PHQ-9上得分明显高于GIM对手.
- 与GIM患者相比,没有先前焦虑史的PASC患者在GAD-7上得分明显高,但在PHQ-9上得分不高.
- 这些发现表明,在PASC患者中,新出现的焦虑和抑郁的负担可能更重.
结论:
- PASC对心理健康的影响,特别是焦虑和抑郁,在没有这些疾病病史的人群中可能更严重.
- 帕斯克患者可能会经历更多的新发展的焦虑和抑郁症状负担.
- 需要进一步的研究来了解PASC患者的长期心理健康轨迹.
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