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在体内对cDC1交叉启动诱导的新抗原进行疫苗接种

Emily S Clark1, Ana Paula Benaduce1,2, Wasif N Khan1

  • 1Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 1550 NW 10th Avenue Medical Campus, Papanicolaou Building 257, Miami, FL, 33136, USA.

Cancer immunology, immunotherapy : CII
|January 17, 2024
PubMed
概括

一个新的抗体平台有效地将TAP siRNA向常规的1型树突细胞 (cDC1) 用于癌症免疫治疗. 这种方法选择性地降低cDC1中的TAP,比以前的方法更有效地抑制瘤生长.

关键词:
癌症疫苗 癌症疫苗 癌症疫苗树突性细胞 树突性细胞新抗原是一种新抗原.与抗原呈现相关的载体 (TAP)siRNA 是一个RNA.

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