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天然深层乳化溶剂用于生物活性低分子量碳水化合物的可溶性和选择性分离
Ignacio Jiménez-Amezcua1,2, Manuel Ignacio López Martínez1, Ana Isabel Ruiz Matute1
1Instituto de Química Orgánica General (IQOG-CSIC), Juan de la Cierva 3, 28006 Madrid, Spain.
Foods (Basel, Switzerland)
|January 17, 2024
概括
天然深层欧特溶剂 (NADESs) 有效地分解生物活性碳水化合物. 基于胆化物的NADES可选择性地将酶与酶分开,使乳糖等有价值化合物的丰富成为可能.
科学领域:
- 绿色化学 绿色化学
- 碳水化合物化学 碳水化合物化学
- 生物分离 生物分离
背景情况:
- 天然深层水溶剂 (NADES) 是环保的溶剂,具有提取生物活性化合物的潜力.
- 关于低分子量碳水化合物 (LMWC) 在NADESs中的溶解度的数据有限.
- 有效的碳水化合物分成方法对于食品和制药应用至关重要.
研究的目的:
- 在NADESs中为LMWC提供新的溶解度数据.
- 探索NADES用于有效分化生物活性碳水化合物.
- 为了研究和的选择性分离.
主要方法:
- 在三个NADES中研究了单糖和二糖的溶解性:胆:2-乙烯基醇 (ChCl:EtG),胆:甘油 (ChCl:Gly) 和胆:乙二氧化酸 (ChCl:Eth).
- 评估了NADESs在选择性碳水化合物分化方面的潜力,重点关注酶/酶分离.
- 使用ChCl:EtG量化了乳糖的丰富.
主要成果:
- 由于其酸性,ChCl:Eth会导致碳水化合物的降解.
- 在二元混合物 (例如乳糖/乳糖,塔加/银糖) 中,ChCl:EtG和ChCl:Gly选择性地从阿尔多中分离了酶.
- 在纯化样本中,ChCl:EtG使乳糖从25%到56%的含量增加,这证明了它对营养药的有用性.
结论:
- NADESs,特别是ChCl:EtG和ChCl:Gly,对于选择性碳水化合物分离是有效的.
- 这些溶剂提供了一种绿色方法,可以从复杂的混合物中分离出有价值的碳水化合物.
- 在食品科学,工程和制药行业中,NADES具有显著的潜力,用于增值碳水化合物加工.
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