在秘鲁利马的成年人中,与COVID-19死亡率相关的并发症:回顾性队列研究
M Gabriela Soto-Cabezas1, Mary F Reyes-Vega1, Anderson N Soriano-Moreno1
1Centro Nacional de Epidemiología, Prevención y Control de Enfermedades, Ministerio de Salud. Lima, Perú.
慢性神经病,病,肝病和癌症显著增加了所有年龄组住院成人的COVID-19死亡风险. 年轻成年人 (18-29岁) 面临这些并发病的最高死亡风险.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 虽然COVID-19大流行不成比例地影响了老年人,但了解年轻人群中的风险因素至关重要.
- 识别与COVID-19死亡率相关的并发症对于有针对性的公共卫生干预至关重要.
研究的目的:
- 评估因COVID-19而住院的成年患者与死亡相关的并发症.
- 根据特定年龄组分析这些关联:年轻人 (18-29岁),成年人 (30-59岁) 和老年人 (≥60岁).
主要方法:
- 一项回顾性队列研究分析了在秘鲁利马和卡拉奥住院的COVID-19患者的数据 (2020年3月至10月).
- 使用具有强大的方差的Poisson回归模型来估计与并发症相关的死亡率的相对风险.
- 为了分析,患者被分为三个年龄组.
主要成果:
- 老年人呈现出最高的COVID-19死亡率 (63.7%),其次是成年人 (27.1%) 和年轻人 (8.5%).
- 慢性神经病,病,肝病和癌症独立地与所有年龄组的死亡风险增加有关.
- 特定的并发症,如心血管疾病,肥胖,糖尿病,慢性肺病和免疫缺陷,也被确定为不同年龄段的风险因素,年轻人患并发症的风险更高.
结论:
- 慢性神经,和肝脏疾病以及癌症是住院成人的COVID-19死亡率的重要风险因素.
- 与并发症相关的风险在最年轻的成年人群 (18-29岁) 中显著更高.
- 这些发现有助于识别高风险患者群体,以定制COVID-19管理策略.
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