睡眠与昼间皮质醇节律的关系,考虑到睡眠测量和皮质醇采样方案
Kaige Guo1, Xiaolin Zhao1, Jiahao Luo1
1Faculty of Psychology, Southwest University, Chongqing 400715, China; Key Laboratory of Cognition and Personality, Southwest University, Chongqing 400715, China.
Psychoneuroendocrinology
|January 17, 2024
概括
客观地衡量,更好的睡眠质量与更健康的白天皮质醇节律有关,包括更强的皮质醇唤醒反应和更的斜坡. 每天四个唾液样本足以进行分析.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠科学 睡眠科学
- 时间生物学 时间生物学
背景情况:
- 以前关于睡眠和白天皮质醇节律的研究是不一致的.
- 混因素包括睡眠测量方法 (特征/状态,客观/主观) 和皮质醇采样方案.
研究的目的:
- 为了研究睡眠与第二天白天皮质醇节律之间的关系.
- 确定测量睡眠和皮质醇的最佳方法,以澄清这些关联.
- 建议具有成本效益的皮质醇采样时间表和计算方法.
主要方法:
- 79名大学生接受了为期3天的动图,以客观评估睡眠.
- 通过睡眠日记记录主观睡眠参数.
- 每天收集六个唾液皮质醇样本,并分析了六个采样方案.
- 一个多层模型检查了特征和状态睡眠对白天皮质醇节律的影响.
- 有两种方法计算了白天皮质醇斜率 (DCS).
主要成果:
- 更高的客观睡眠效率和总睡眠时间 (状态和特征) 与更高的皮质醇唤醒反应 (CAR),更高的清醒皮质醇水平和更的DCS有关.
- 建议至少每天抽取四份唾液样本 (清醒时,30分钟,1小时,睡前) 进行综合分析.
- 特定的斜率计算方法 (高峰到床的睡眠效率,起床到床的总睡眠时间) 被认为是有效的.
结论:
- 客观的睡眠质量显著影响第二天的白天皮质醇节奏.
- 至少每天四次皮质醇样本和特定的斜率计算方法可以可靠地评估这些关系.
- 这项研究提供了对睡眠-皮质醇动态的更清晰的理解,并为未来的研究提供了实际指导方针.
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