美国成年人腹部肥胖和心脏代谢疾病的严重程度
1School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Public health
|January 17, 2024
概括
心脏代谢性疾病 (CMD) 在患有腹部肥胖的成年人中非常普遍. 腹部肥胖症的严重程度增加显著提高CMD流行率和所有原因的死亡风险.
科学领域:
- 公共卫生 公共卫生
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 腹部肥胖是心脏代谢性疾病 (CMD) 的重要危险因素.
- 了解基于腹部肥胖严重程度的CMD的患病率和风险分层对于公共卫生干预至关重要.
研究的目的:
- 确定各种心脏代谢疾病 (CMD) 在患有腹部肥胖的成年人中的患病率.
- 评估是否区分腹部肥胖症的严重程度是必要的风险评估.
主要方法:
- 利用了国家健康和营养检查调查 (NHANES) 数据 (2011-2020年用于横截面,1988-2018年用于预期死亡率).
- 根据腰围三角形,将腹部肥胖症分为I,II和III类.
- 采用Poisson回归和Cox比例危险模型来分析按肥胖严重程度的CMD流行率和死亡风险.
主要成果:
- 超过57%的23,168名成年人患有腹部肥胖;观察到高CMD患病率 (例如,糖尿病17.3%,高血压39.3%,脂质失调59.5%).
- 超过一半 (55.5%) 患有两个或两个以上的CMD.
- 与I类相比,III类腹部肥胖症的患病率高出43%-184%,全因死亡风险增加44%.
结论:
- 心脏代谢性疾病很常见,在美国成年人中经常与腹部肥胖一起发生.
- 腹部肥胖症的严重程度是CMD患病率和死亡风险的重要决定因素,强调需要差异化风险评估.
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