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儿科先天性微病的重建技术:系统审查和元分析

Hugh Andrew Jinwook Kim¹, Amirpouyan Namavarian¹, Urooj Khan¹

¹Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.

Facial plastic surgery : FPS

|January 17, 2024

概括

自体移植和全体移植在儿科微病重建方面显示了类似的满意度和并发症率. 对年轻患者和当需要同时恢复听力时,偏好Allografts.

科学领域:

整形外科整形外科整形外科
耳鼻喉科耳鼻喉科耳鼻喉科
儿科先天性重建儿科先天性重建

背景情况:

自体移植和全体移植是微重建的标准材料.
需要进行系统审查,以比较它们在儿科患者中的疗效.

研究的目的:

系统地审查和比较用于儿科先天性微病重建的自体移植和异体移植.
分析患者的人口统计,微病的严重程度,手术方法和结果.

主要方法:

在MEDLINE,Embase,PubMed,Web of Science和CINAHL数据库中的系统文献搜索 (开始2021).
使用随机效应模型对聚合比例和连续变量的元分析.
微等级 (高/低) 的分层和自移植和全移植组之间的比较.

主要成果:

68项研究包括5546名儿科患者 (5382名自体移植,164名全体移植).
所有移植组较年轻 (8.4岁对11.1岁),微病度较高 (98%对72%),综合征患者较少 (0%对43%).
两组的满意度 (>90%) 和并发症率 (<10%) 是相似的;所有移植有利于并发性动脉增生/骨传导植入物.

结论:

自体移植和全体移植在儿科微病修复中产生了可比的满意度和并发症率.
对年轻患者和联合听力恢复手术来说,异构移植是有利的.
需要进一步的大规模研究来确定长期的结果.

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