含有氨酸的化物漆的化物释放潜力
Nouf Ali Alblooshi1, Jogikalmat Krithikadatta2, Cynthia Yiu3
1Paediatric Dentistry, Department of Clinical Sciences, College of Dentistry, Ajman University.
Dental materials journal
|January 17, 2024
概括
将L-氨酸 (Arg) 纳入化物 (F) 漆中,可以显著增强随着时间的推移释放的F. 这项研究表明,含有的涂料可为牙科应用提供更多的化物可用性.
科学领域:
- 牙科材料科学 牙科材料科学
- 化物化学 化物化学
- 生物材料是一种生物材料.
背景情况:
- 化物漆对于预防脏至关重要.
- 从牙漆中优化化物释放是一个正在进行的研究领域.
- L-氨酸在调节口腔环境方面表现出潜力.
研究的目的:
- 调查L-氨酸在商业化漆中化物释放的L-氨酸结合的影响.
- 在7天的时间内量化离子释放动力学.
- 评估L-氨酸对漆的pH值和无机化物提取的影响.
主要方法:
- 四种商业化物涂料通过加入L-氨酸 (2% w/v) 来进行修改.
- 用离子选择性电极在多个时间点 (1小时至7天) 测量化物释放.
- 分析了漆介质的pH值和初级无机化物提取.
主要成果:
- 化物释放和集成平均/累积化物释放在含有Arg的漆中明显高于对照组 (p<0.01).
- 料介质的pH值受到Arg结合的显著影响.
- 在Arg组中,初级提取的化物度明显较低,表明化学相互作用 (p<0.001).
结论:
- 加入L-氨酸显著提高了化漆的化释放潜力.
- 和化物之间的化学相互作用影响释放动力学和可用性.
- 基化漆是一种有前途的策略,可以改善皮的预防.
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