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通过重力测量和产品控制来检测和减少亲肠道营养中错误的复合
Daniel Gómez-Costas1, Rosa María Romero-Jiménez1, Maria Elena Lobato-Matilla1
1Hospital General Universitario Gregorio Marañón, Hospital Pharmacy, ES 28007, Spain.
概括
一个强大的质量控制系统对肠外营养显著减少了准备错误. 这种有效,易于实施的工具通过在复合中最大限度地减少重力测量和产品相关错误来提高患者的安全性.
科学领域:
- 制药复合剂 制药复合剂
- 医疗保健中的质量控制
- 父母肠道营养是一种营养.
背景情况:
- 腹腔营养 (PN) 准备是复杂的,容易出现错误.
- 有效的质量控制 (QC) 对PN复合中的患者安全至关重要.
- 之前的研究强调,需要对制药服务进行严格的监测.
研究的目的:
- 分析通过重力测量和产品质量控制检测到的腹营养制剂中的错误.
- 将当前的错误率与质量控制系统初始实施阶段的错误率进行比较.
- 评估已建立的质量控制流程在减少PN制备错误方面的有效性.
主要方法:
- 在2019-2021年期间,对儿科和成人PN准备中的错误进行前性分析.
- 质量控制包括视觉检查,重力测量控制 (±5%的理论重量偏差) 和产品控制.
- 与2016-2018年数据相比,错误按类型和涉及的组件进行分类和分析.
主要成果:
- 在41,809种PN制剂中,发现了345个错误 (0.83%).
- 确定了重力测量错误 (193) 和产品错误 (152),电解质在产品错误中很常见.
- 与实施阶段相比,总错误的显著减少 (0.71%) 被观察到 (P < .05).
结论:
- 亲肠道营养的全面质量控制是很容易实现和有效的.
- 建立的质量控制系统成功地检测并防止了重大准备错误.
- 这种质量控制过程的广泛采用导致了整体错误率的显著降低.
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