术后的并发症 术内X射线辐射治疗的乳房切除术后的术后并发症:一项回顾性比较研究
Hadas Kadar Sfarad1, Tanir M Allweis2
1Department of General Surgery, Kaplan Medical Center, Rehobot, Israel.
Clinical breast cancer
|January 17, 2024
概括
早期乳腺癌的手术内辐射 (IORT) 显示的并发症率高于单独的外部束辐射疗法 (EBRT) 或瘤切除术. 大多数并发症都是轻微的和短暂的,但患者和医生教育是管理的关键.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 辐射瘤学 辐射瘤学
背景情况:
- 术内辐射 (IORT) 是早期乳腺癌的新兴治疗方法,经常取代外部束辐射疗法 (EBRT).
- 虽然IORT提供有针对性的辐射,但对其术后并发症的数据有限.
- 这项研究旨在比较IORT与传统治疗的并发症率.
研究的目的:
- 为了比较术后并发症的发生率,用IORT进行淋巴切除术与用EBRT或单独进行淋巴切除术进行淋巴切除术相比.
- 为了确定与每种治疗方式相关的特定并发症.
主要方法:
- 对445名接受IORT,EBRT或单独进行淋巴切除术的患者进行了回顾性审查.
- 数据收集包括临床,人口和组织病理信息.
- 在三个治疗组中,术后并发症率的比较.
主要成果:
- 接受IORT的患者患血清瘤 (65%vs34%vs11%),手术部位感染 (23%vs15%vs6%),红血瘤 (34%vs16%vs6%) 和轻微并发症 (55%vs47%vs17%) 的比率高于单独接受EBRT和隆瘤切除的患者.
- 这些差异的P值具有统计学意义 (P = .000对于血清瘤和红斑,P = .013对于感染).
- 平均随访时间为14个月.
结论:
- 术内辐射 (IORT) 与术后并发症的发病率较高,与单独的外部束辐射疗法 (EBRT) 或瘤切除术相比.
- 大多数这些并发症都是轻微的和暂时的.
- 报告的增加可能与IORT的新性有关;医生和患者的教育可以改善并发症管理.
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