在儿童白内障手术后,长期风险的青光眼在儿童白内障手术后
Diana Chabané Schmidt1, Frank Eriksson2, Daniella Bach-Holm1,3
1Department of Ophthalmology, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Acta ophthalmologica
|January 17, 2024
概括
儿童白内障手术显著增加了晚年患青光眼的风险. 终身监测对于早期检测和预防视力丧失至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
- 公共卫生 公共卫生
背景情况:
- 儿童白内障手术是一种常见的手术.
- 长期的后果,特别是青光眼的风险,尚未完全理解.
- 遗传因素可能在儿童白内障和二次绿内障中发挥作用.
研究的目的:
- 为了调查儿童时期进行的白内障手术后长期出现的绿内障的发病率.
- 为了识别早期白内障手术后与绿内障发展相关的潜在风险因素.
主要方法:
- 研究了一组68名来自遗传性白内障家庭的患者,这些患者在18岁之前接受了手术.
- 眼科检查和医疗记录的审查被用来诊断青光眼或眼睛高血压 (OHT).
- 使用生存分析和考克斯回归模型来评估长期风险并确定相关因素.
主要成果:
- 随访时间中位数为35年,白内障手术的中位数年龄为7年.
- 15名患者 (22%) 患有青光眼或OHT,70岁时累计风险为47.7%.
- 没有发现青光眼/OHT与性别,手术时的年龄,之前的眼科干预次数或青光眼家族史之间有显著的关联.
结论:
- 儿童白内障手术与成年人患青光眼的重大风险有关.
- 在这些患者中,定期,终身的眼科随访对于早期诊断和治疗绿眼病至关重要.
- 这突显了儿童白内障手术后眼睛并发症的持续监测的重要性.
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