静脉壁厚度和由于SARS n-cov2病毒感染的肺部感染的严重程度
Gennaro Quarto1, Giacomo Benassai2, Annamaria Colao2
1Department of Clinical Medicine and Surgery, Federico II University, Via Sergio Pansini 5, 80131, Naples, Italy. gquarto@unina.it.
Journal of translational medicine
|January 17, 2024
概括
从COVID-19中康复的患者显示静脉壁厚度增加 (VWT) 与肺损伤严重程度相关. 这表明COVID-19血管效应的微血栓和炎症过程的共同起源.
科学领域:
- 血管医学 血管医学
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
背景情况:
- 由SARS-CoV-2引起的COVID-19可能导致长期的血管并发症.
- 在COVID-19患者中,肺部感染的严重程度有很大的不同.
- 了解COVID-19后的血管变化对于患者管理至关重要.
研究的目的:
- 调查静脉壁厚度 (VWT) 与COVID-19幸存者的肺部感染严重程度之间的关系.
- 探索COVID-19中血管和肺损伤的潜在常见病理机制.
主要方法:
- 对31名COVID-19康复患者的观察性研究.
- 用超声波测量常见的股骨和骨静脉壁厚度 (VWT).
- 使用CT评分系统和CEAP-C类计算量化肺损伤.
主要成果:
- 与VWT<1毫米 (3.82) 患者相比,VWT>1毫米的患者的COVID平均得分 (7.4) 显著高于VWT<1毫米 (3.82) 的患者.
- 在静脉壁厚度和COVID分数之间发现了统计学上显著的直接关系.
- 这些发现表明静脉壁变化与COVID-19后肺损伤程度之间的相关性.
结论:
- 静脉壁厚度变化与COVID-19患者肺部感染严重程度之间存在联系.
- 微血栓和炎症过程可能是SARS-CoV-2感染中血管和肺病理的常见发起因素.
- 对COVID-19的血管后果进行进一步的研究是有必要的.
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