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母亲补充康杰克葡萄甘可以改善母体微生物群,使哺乳期的后代更健康

Feng Gao¹, Wentao Zhang¹, Mingming Cao¹

¹College of Animal Science and Technology, Northeast Agricultural University, Harbin, China.

Journal of the science of food and agriculture

|January 18, 2024

概括

在孕期晚期和哺乳期服用母乳康杰克葡萄甘 (KGM) 补充剂改善了母猪的营养状况和牛奶质量. 这种饮食干预通过调节母体肠道微生物群和料摄入激素来增强后代的抗炎能力.

科学领域:

营养科学营养科学
微生物组研究微生物组研究
母婴健康孕产妇和子女的健康

背景情况:

母亲的饮食极大地影响后代的健康.
康杰克葡萄甘 (KGM) 是一种功能性多糖,具有抗氧化和益生菌性质.
对KGM在孕产妇营养中的作用的有限理解需要进一步的研究.

研究的目的:

调查孕期晚期和哺乳期母体KGM补充剂的影响.
评估对母亲和后代的好处.

主要方法:

在怀孕晚期和哺乳期对KGM的母体补充.
对血清脂质概况和抗氧化能力的分析.
测量与料摄入相关的激素 (NPY,格林,AMPK).
便微生物组分析 (细菌属,短链脂肪酸).
评估牛奶和后代血清炎症标志物 (IL-6,IL-10,佐努林).

主要成果:

KGM改善了母体血清LDL-C和抗氧化能力.
KGM增加了料摄入的激素 (NPY,格林,AMPK) 和改变了肠道微生物群的组成 (克洛斯特里,Candidatus Saccharimonas,Firmicutes,Christensenellaceae).
KGM增加了有益的便短链脂肪酸 (乙酸,酸,异酸).
KGM降低了牛奶IL-6,增加了牛奶IL-10,并降低了后代血清佐努林.

结论:

孕产妇KGM补充剂通过微生物组调节和增加料摄入量来提高孕产妇的营养状况.
补充KGM可以提高后代血清的抗炎能力.
KGM显示出作为改善母亲和后代健康结果的饮食策略的潜力.

关键词:

料摄入量料摄入量康杰克葡萄康曼南 (glucomannan) 是一种葡萄糖.孕产妇营养孕产妇营养后代的后代是一个后代.

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