结肠镜后结肠直肠癌的发生率,特征和预测因素
Sandra Baile-Maxía1, Carolina Mangas-Sanjuan1, Noelia Sala-Miquel1
1Gastroenterology Department, Hospital General Universitario Dr. Balmis, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain.
United European gastroenterology journal
|January 18, 2024
概括
结肠镜后结肠直肠癌 (PCCRC) 影响了4.1%的病例,由于准备不足或断片多角切除术,在结肠镜期间经常错过. 早期检测和改进的结肠镜技术对于降低PCCRC率至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 结肠镜后结肠直肠癌 (PCCRC) 被定义为结肠镜检查后诊断的结肠直肠癌 (CRC),没有发现恶性病变.
- PCCRC已经成为评估结肠镜检查程序质量和癌症检测率的关键指标.
研究的目的:
- 为了确定PCCRC的发病率.
- 描述PCCRC的特征,包括位置和阶段.
- 确定与PCCRC发展相关的与索引结肠镜相关的预测因素.
主要方法:
- 从2015年到2018年进行了一项多中心,观察性,回顾性研究.
- 在结肠镜检查后的10年内计算PCCRC率.
- 根据病因对PCCRC病例进行了分类,并与根据人口统计和结肠镜检查细节匹配的对照组进行了比较.
主要成果:
- 该研究在101524次结肠镜检查 (0.1%) 中发现了107例PCCRC病例.
- 一,三,五和十年的PCCRC率分别为0.4%,2.2%,3.1%和4.1%.
- 不充分的肠道准备 (OR3.05) 和断片多角切除术 (OR19.89) 与PCCRC有显著的关联.
结论:
- 在研究人群中,大约4.1%的结直肠癌病例被归类为PCCRC.
- 显著比例的PCCRC被归因于错过的病变,特别是在右结肠,尽管有足够的肠道清洗.
- 诸如肠道准备不足和指数结肠镜检查期间的断片多角切除等因素是PCCRC的关键预测因素.
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