住院儿科患者中与使用抗菌素有关的问题:一项前性观察性研究
Kidu Gidey1, Solomon Girmay Aregawi1, Berhane Yohannes Hailu1
1Department of Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Infection and drug resistance
|January 18, 2024
概括
超过一半的住院儿科患者经历了与抗微生物药物使用有关的问题,包括不必要的或额外的治疗. 伴随性疾病和更长的住院时间增加了这些风险,突出了需要更好的抗菌药物管理的需要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 儿科医学 儿科医学
- 传染性疾病 传染性疾病
背景情况:
- 滥用抗微生物药物是一个全球性的健康问题,有助于抗微生物药物耐药性.
- 关于儿童群体,特别是发展中国家的抗微生物药物使用相关问题的数据有限.
研究的目的:
- 确定住院儿科患者中与抗微生物药物使用相关问题的流行率.
- 确定与儿科患者这些问题相关的风险因素.
主要方法:
- 在埃塞俄比亚的艾德综合专科医院进行了前性观察性研究.
- 包括2019年9月至11月期间因传染病住院的儿科患者 (≤15岁).
- 收集关于患者人口统计,诊断和抗菌药物治疗的数据,以确定与使用相关的问题.
主要成果:
- 总共有232名儿科患者被录取;53.9%的人至少遇到了一种与使用抗微生物药物相关的问题.
- 最常见的问题是不必要的抗微生物治疗 (22.8%) 和需要额外的抗微生物治疗 (16.4%).
- 伴随性疾病 (AOR: 1.84) 和住院超过一周 (AOR: 1.88) 是这些问题的重要预测因素.
结论:
- 在这种环境中,住院儿科患者中,与抗菌素使用相关的问题很普遍.
- 干预措施应侧重于有针对性的教育,抗菌药物管理和负责任的处方实践.
- 加强儿科护理和协作努力对于缓解这些问题至关重要.
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