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Updated: Jul 5, 2025

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CryoVirusDB:一个标记的Cryo-EM图像数据集用于人工智能驱动的病毒粒子挑选

Rajan Gyawali1,2, Ashwin Dhakal1,2, Liguo Wang3

  • 1Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA.

bioRxiv : the preprint server for biology
|January 18, 2024
PubMed
概括

研究人员创建了CryoVirusDB,这是从电子冷显微镜 (cryo-EM) 图像中标记病毒颗粒的数据集. 此资源有助于人工智能开发用于病毒结构的确定.

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Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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