患有高血压的患者过度白天嗜睡:系统性审查
Yazeed Almansouri1, Abdulrahman Alsuwatt1, Mazen Alzahrani1
1Medicine, Taif University, Taif, SAU.
Cureus
|January 18, 2024
概括
过度白天嗜睡 (EDS) 在高血压患者中很常见,患病率从12.1%到88.3%不等. 诸如老年和肥胖等因素与高血压中的EDS有关,这突显了严重的健康问题.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 经常出现亚临床病例,经常通过像打和过度白天嗜睡 (EDS) 这样的症状来确定.
- 过度的白天嗜睡 (EDS) 是在被诊断为高血压 (HTN) 的患者中观察到的普遍症状.
研究的目的:
- 进行现有文献的系统审查,以确定高血压患者中过度白天嗜睡 (EDS) 的患病率和相关性.
主要方法:
- 在主要的数据库中进行了系统的文献搜索:PubMed,SCOPUS,Web of Science和Science Direct.
- 瑞安QRCI软件用于研究选择和数据管理.
- 包含58,517名患者的9项研究被纳入最终分析.
主要成果:
- 高血压患者中EDS的患病率差异很大,从12.1%到88.3%不等.
- 与正常血压患者相比,高血压患者的EDS表现更差.
- 高血压患者的EDS相关因素包括年龄较大,教育程度较低,超重状态,就业,肥胖,抑郁和高血压持续时间较长. 在某些情况下,还注意到了交管失衡.
结论:
- 过度的白天嗜睡 (EDS) 是高血压 (HTN) 患者的重要和常见问题.
- 几种人口,临床和生活方式因素与该人口中的EDS有关,表明需要有针对性的查和管理策略.
相关概念视频
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
63
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
63
Insufficient Sleep and Sleep Deprivation
145
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
145
Sleep Apnea
157
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
157
Narcolepsy
103
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
103
Sedatives and Hypnotics Drugs: Miscellaneous Agents
176
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
176
Management of Insomnia
252
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
252


