住院COVID-19患者的新发作;系统性审查和元分析
Daniah Shamim1, Fatima Ganatra2, Murtaza Khan1
1Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
The Neurohospitalist
|January 18, 2024
概括
新发作发作发生在住院COVID-19患者的0.71%. 在这些患者中,不到一半的患者表现出脑部成像异常,很少有人符合COVID-19脑炎的标准.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 发作是COVID-19住院患者常见的神经复杂症之一.
- 了解新发作发作的发生率对于管理这些患者至关重要.
研究的目的:
- 确定COVID-19住院成年患者中新发作发作的频率.
- 分析相关的神经学发现和并发症.
主要方法:
- 进行了对15项队列研究的系统审查和元分析.
- 分析了28242名住院COVID-19患者的数据.
- 用一个随机效应模型对单一比例的逆方差元分析.
主要成果:
- 在COVID-19患者中,急性症状的总体频率为0.71% (95%CI:0.32-1.25).
- 在完成EEG的患者中,发作风险为8.49% (95%CI:0.62-24.07).
- 在45.7%的发作患者中,急性神经影像异常存在,通常是血管攻击. 只有2.8%的人符合COVID-19脑炎的标准.
结论:
- 住院COVID-19患者中发作的发生率相对较低,为0.71%.
- 神经成像异常常见于COVID-19患者经历发作.
- 在这个患者群体中,COVID-19脑炎是不常见的诊断.
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