探索COVID-19和没有COVID-19康复的精神分裂症患者的认知功能的关系
Anam Mehmood1, Ali Madi Almajwal2, Abdullah Addas3,4
1Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Frontiers in public health
|January 18, 2024
概括
在精神分裂症患者中,COVID-19感染显著恶化了认知功能,特别是工作记忆和注意力. 失眠成为导致感染后认知缺陷的关键因素.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- 精神分裂症患者表现出认知缺陷,可能会被COVID-19加剧.
- 疫情对这种脆弱人群的认知功能的影响需要进行调查.
研究的目的:
- 为了比较COVID-19感染前后的精神分裂症患者的认知表现.
- 在精神分裂症中确定COVID-19后与认知变化相关的因素.
主要方法:
- 在219名精神分裂症患者的长度队列研究 (2022年6月至2023年5月).
- 参与者分为COVID-19感染者 (n=165) 和非感染者 (n=54) 组.
- 使用精神分裂症认知简要评估 (BACS) 评估认知功能,以及其他临床尺度.
主要成果:
- 感染COVID-19的患者在全球功能,工作记忆,运动速度和注意力方面表现出显著的认知衰退 (p<0.001).
- 失眠 (β=0.411) 和与COVID-19的基线认知相互作用 (β=0.796) 与认知缺陷有关.
- 在全球认知和临床症状,自主性或抑郁症之间没有发现显著的关联.
结论:
- COVID-19对精神分裂症患者的认知功能产生了负面影响.
- 在这种情况下,失眠是认知障碍的主要决定因素.
- 需要进一步的研究来了解COVID-19在精神分裂症中的多样性认知影响.
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