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Xiaohui Yao^1,2, Qikai Yin¹, Xiaodong Tian³

¹Department of Arbovirus, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Frontiers in cellular and infection microbiology

|January 18, 2024

概括

在中国,广泛的海迪病毒 (HEDV) 和无锡病毒 (WUXV) 感染在人类和动物中被发现. 这项首次血清流行病学研究强调了狗和中HEDV和WUXV的显著流行率.

科学领域:

病毒学病毒学
流行病学流行病学
动物传播疾病动物传播疾病

背景情况:

赫迪病毒 (HEDV) 和无锡病毒 (WUXV) 是新发现的沙传播的布尼亚病毒.
扩大地理分布和严重神经症状 (老鼠的WUXV) 的可能性需要了解它们在哺乳动物宿主中的流行程度.
关于HEDV和WUXV在人类和动物群体中的血清流行情况的数据有限.

研究的目的:

确定人类,狗和中HEDV和WUXV的感染状况,这些病毒已被隔离的地区.
为了对这两种特定的沙传播病毒进行首次血清流行病学调查.

主要方法:

采用西式涂抹技术检测针对HEDV和WUXV的IgG抗体.
从发烧患者,养狗和居住在受影响地理区域的身上采集了血清样本.

主要成果:

人类血清样本显示HEDV的阳性率为17.24%,WUXV的阳性率为68.96%.
狗血清表现出高的阳性率:HEDV的87.10%,WUXV的70.97%.
鸟类血清 () 显示的阳性率为HEDV的47.22%和WUXV的52.78%.

结论:

该研究证实,在研究区域中,人类,狗和的HEDV和WUXV感染普遍存在.
与人类相比,当地动物 (狗和) 的HEDV感染率明显高.
这些发现为中国的载体传播和动物感染病毒感染提供了关键的见解,并为全球沙传播病毒的研究提供了参考.

关键词:

中国中国中国中国.黑迪病毒黑迪病毒这就是Phenuiviridae.无锡的病毒无锡病毒感染了沙病毒的感染.血清发生率的普遍性.动物性传染病原体的病原体

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