基于年龄和炎症标志物预测结肠直肠癌中长期术后阴茎的诺莫克拉姆
Zong-Qi Fan1, Yang Chen2, Xin-Ao Fu2,3
1Department of Gastrointestinal Surgery, Chaoyang Central Hospital Postgraduate Training Base of Jinzhou Medical University, Liaoning Province, 122000, PR China.
Biomarkers in medicine
|January 18, 2024
概括
这项研究确定了年龄和中性粒细胞 - 淋巴细胞比率的变化作为长期术后阴茎 (PPOI) 的关键预测因素. 一个新的名图可以帮助临床医生个性化PPOI诊断和治疗策略.
科学领域:
- 胃肠病学 胃肠病学
- 外科手术的结果
- 炎症标记物 炎症标记物
背景情况:
- 长期的手术后阴道 (PPOI) 是腹部手术后的常见并发症,导致发病率增加和医疗费用增加.
- 确定可靠的PPOI预测因子对于主动的临床管理和改善患者的治疗结果至关重要.
研究的目的:
- 研究特定炎症标志物与PPOI发展之间的关联.
- 根据已识别的风险因素,开发和验证PPOI的预测名录.
主要方法:
- 对接受腹部手术的229名患者的数据进行了回顾性分析.
- 单变量和多变量逻辑回归分析以确定PPOI的独立风险因素.
- 开发的预测名录的内部验证.
主要成果:
- PPOI的发生率为38.0% (229名患者中有87名).
- 年龄,手术前的中性粒细胞-淋巴细胞比率 (NLR) 和NLR的变化被确定为PPOI的独立风险因素.
- 建立的名录表显示出良好的预测性能.
结论:
- 使用年龄和NLR相关因素开发的诺米图,可以有效预测PPOI.
- 该工具有可能在临床实践中指导PPOI的个性化诊断和治疗策略.
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