相关实验视频

Updated: Jul 5, 2025

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

主要肝脏不分化的多形肉瘤与复发和广泛转移的转移

Huabo Sun¹, Bingchang Ge², Jun Li³

¹Gastroenterology, Yantai Affiliated Hospital of Binzhou Medical University.

Revista espanola de enfermedades digestivas

|January 18, 2024

概括

通过手术切除了一种罕见的无差异化肝脏形肉瘤. 尽管进行化疗,但仍观察到术后复发和进展,这凸显了治疗这种侵袭性肝癌的挑战.

科学领域:

肝胆道手术肝胆道手术
手术病理学手术病理学
在瘤学瘤学.

背景情况:

一名59岁的男性出现了一种偶然发现的无症状肝脏质量.
标准瘤标志物在正常范围内.
图像检查显示有5.0厘米的低密度肝损伤.

研究的目的:

报告一种罕见的无差异化形性肝脏肉瘤病例.
讨论与这种恶性瘤相关的诊断和治疗挑战.

主要方法:

诊断通过部分肝切除术和详细的基因病理学检查与免疫组织化学证实.
手术后的治疗包括使用卡雷利祖马布和格姆奇塔的化疗.

主要成果:

病理学发现不分化形肉瘤具有特定的免疫组织化学标记 (Vimentin+, CK-, CD68+, INI-1+, SMA+, Ki67 50%+).
手术后三个月,MRI显示复发与结节和边缘状增强.
手术后六个月,CT扫描显示了明显的疾病进展.

结论:

肝脏未分化形肉瘤是一种具有不良预后的侵袭性恶性瘤.
这一案例凸显了尽管采用多模式治疗,但在治疗复发性肝脏肉瘤方面面临的挑战.

更多相关视频

A Preclinical Murine Model of Hepatic Metastases

A Preclinical Murine Model of Hepatic Metastases

Published on: September 27, 2014

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Published on: January 25, 2015

相关概念视频

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...