食道重塑与儿科埃索诺菲尔食道炎的饮食行为相关
Kanak V Kennedy1, Chizoba N Umeweni1, Maiya Alston1
1Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
The American journal of gastroenterology
|January 18, 2024
概括
患有性食道炎 (EoE) 的儿科患者表现出改变的饮食行为,包括增加和更长的摄入时间. 这些变化甚至在缓解后仍然存在,可能与食道延展能力的降低有关.
科学领域:
- 胃肠病学 胃肠病学
- 儿科医学 儿科医学
- 临床营养学 临床营养学
背景情况:
- 有限的数据存在于儿童异性食道炎 (EOE) 的饮食习惯.
- 了解饮食行为对于管理儿童的EoE至关重要.
- 以前的研究并没有广泛地将饮食行为与儿科EoE的临床发现相关联.
研究的目的:
- 为了比较患有EoE的儿科患者的饮食行为与健康对照.
- 评估饮食行为与EoE症状,内镜/组织学发现和食道延展性之间的相关性.
主要方法:
- 展望性,观察性研究设计.
- 评估四种食物质地 (纯制,软固体,可,硬固体) 的饮食行为.
- 收集关于每口的数据,液体,消费时间,症状,内镜,组织学和食道延展性的数据.
主要成果:
- 与对照组相比,儿科EoE患者的每口量显著增加,软固体,可和硬固体食物的消费时间更长.
- 增加的消费时间与更高的内镜评分和减少食道张张能力相关.
- 在活跃和不活跃的EoE之间没有观察到饮食行为的显著差异.
结论:
- 儿科EoE与改变的饮食行为有关,以增加和消费时间为特征.
- 这些行为变化可能会持续,尽管组织学缓解.
- 改变的食道张力似乎是驱动这些饮食行为修改的关键因素.
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