患有类风湿性关节炎和一些相关因素的患者中抑郁障碍的特征

相关实验视频

Updated: Jul 5, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

149

H-T Pham¹, H Vu-Thi, C-T Le

¹Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam. hungnguyen@hmu.edu.vn.

European review for medical and pharmacological sciences

|January 18, 2024

概括

抑郁症在越南的风湿性关节炎 (RA) 患者中非常普遍,影响超过76%的患者. 疾病活动增加与抑郁症严重程度相关,对生活质量产生负面影响.

科学领域:

类风湿病学类风湿病学
精神病学是一个精神病学.
公共卫生公共卫生

背景情况:

类风湿性关节炎 (RA) 是一种慢性炎症状况,具有显著的身体和心理影响.
抑郁症是RA患者常见的并发症,影响他们的整体健康和治疗结果.
早期发现和治疗抑郁症对于改善RA患者的生活质量至关重要.

研究的目的:

调查越南RA患者中抑郁症患病率.
确定这一群体中抑郁症的关键特征和相关因素.
为开发有针对性的干预措施提供数据,以改善患者护理.

主要方法:

一项涉及156名使用ACR-1987标准诊断的RA患者的横截面研究.
患者健康问卷-9 (PHQ-9) 用于查抑郁症疾病.
临床数据,包括疾病活动得分 (DAS28-CRP) 和生活质量 (SF-36),以及人口统计和实验室结果进行了分析.

主要成果:

在RA患者中观察到抑郁障碍的高患病率 (76.3%).
49.4%的患者报告中度至重度抑郁,其中91%的患者经历睡眠障碍.
抑郁症的严重程度与RA疾病活动有正相关性,与生活质量有负相关性.

结论:

抑郁症在越南的风湿性关节炎患者中是一个重大而广泛的问题.
在RA中较高的疾病活性与抑郁症严重程度的增加有关.
有效管理RA疾病活动对于缓解抑郁症和提高患者生活质量至关重要.

相关概念视频

01:27

Depressive Disorders: Etiology

102

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

102

01:27

Depressive Disorders: MDD and Dysthymia

136

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

136

01:18

Depression: Overview

247

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

247

01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

01:24

T Cell Types and Functions

1.0K

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

1.0K

01:22

Personality Disorders: Paranoid and Schizoid

Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...