基于脂质和聚合物的纳米载体平台用于癌症疫苗的输送
Suhair Sunoqrot1, Sara A Abdel Gaber2, Razan Abujaber1
1Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.
ACS applied bio materials
|January 18, 2024
概括
纳米技术通过使用基于脂质和聚合物的纳米颗粒来增强免疫系统对抗癌症来增强癌症疫苗. 本综述探讨了用于临床使用的纳米疫苗开发的进展和挑战.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 纳米技术 纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 癌症免疫疗法是治疗抗传统疗法的恶性瘤的一个不断增长的领域.
- 癌症疫苗的目的是刺激患者的免疫系统消除癌细胞.
- 纳米技术为开发先进的癌症疫苗提供了有希望的平台.
研究的目的:
- 审查纳米技术支持的癌症疫苗.
- 突出最近基于脂质和聚合物的纳米疫苗的进展.
- 讨论纳米药物的临床转化中的挑战.
主要方法:
- 关于纳米疫苗的当前文献的审查.
- 专注于基于脂质和基于聚合物的纳米粒子平台.
- 混合纳米疫苗结构的分析.
主要成果:
- 基于纳米粒子的癌症疫苗显示出显著的前景.
- 基于脂质的纳米粒子是先进的输送平台.
- 基于聚合物的纳米粒子也引起了相当大的兴趣.
结论:
- 纳米技术显著推进了癌症疫苗开发.
- 需要进一步的研究来克服临床翻译的挑战.
- 纳米疫苗是未来癌症治疗的一个关键领域.
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