同型氨酸,高同型氨酸血症和H型高血压
Dong-Feng Wu1, Rui-Xing Yin2, Jin-Long Deng1
1Department of Geriatric Cardiology, Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region, 6 Taoyuan Road, Nanning 530021, Guangxi, People's Republic of China.
European journal of preventive cardiology
|January 18, 2024
概括
高水平的homocysteine (Hcy),称为高homocysteinemia (HHcy),与高血压和心血管疾病有关. 本综述详细介绍了Hcy代谢,HHcy和H型高血压 (HTH) 的临床参考.
科学领域:
- 生物化学 生物化学
- 心脏病学 心脏病学
- 临床医学 临床医学
背景情况:
- 同类氨酸 (Hcy) 是一种非必需的氨基酸,来自于甲氨酸代谢.
- 血Hcy水平升高定义了高homocysteinemia (HHcy),一种由饮食,遗传学和酶功能影响的条件.
- H型高血压 (HTH) 涉及与HHcy.同时发生的基本高血压.
研究的目的:
- 系统地审查当前关于同类氨酸,高同类氨酸血症和H型高血压的研究.
- 提供关于Hcy.的来源,代谢和影响因素的临床参考.
- 探索Hcy水平和高血压之间的关系,包括病变和心血管并发症.
主要方法:
- 对最近关于Hcy,HHcy和HTH的研究进行系统的文献综述.
- 专注于Hcy来源,代谢途径和影响血水平的因素.
- 分析Hcy检测方法,HTH病原和心血管风险.
主要成果:
- HHcy被认为是心血管疾病的独立风险因素.
- 异常的Hcy代谢,营养缺乏和遗传因素导致Hcy的升高.
- 在Hcy度和高血压之间存在强烈的关联,定义HTH.
结论:
- 了解Hcy代谢和HHcy对于管理HTH至关重要.
- 在高血压患者中,HHcy有助于心血管并发症.
- 对于HTH诊断和治疗,需要进一步的研究和临床关注.
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