在低风险的早产样本中,杏仁体的结构和功能及其与社会情感结果的关联
L Fernández de Gamarra-Oca1, O Lucas-Jiménez1, J M Ontañón2
1Department of Psychology, Faculty of Health Sciences, University of Deusto, Bilbao, Bizkaia, Spain.
Brain structure & function
|January 18, 2024
概括
低风险的早产并没有影响年轻成年人的社会情感结果或杏仁核体积. 然而,在早产的个体中观察到杏仁体和中部前皮层之间的功能连接 (FC) 增加.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 医疗成像医学成像
背景情况:
- 在早产后的儿童中观察到非典型的杏仁体发育和功能连接 (FC).
- 这项研究调查了这些变化是否在低风险的早产者中持续到年轻成人期.
研究的目的:
- 评估前期出生的年轻成年人与满期的同龄人相比,杏仁体的结构和功能差异.
- 为了检查杏仁体结构/功能和社会情感结果之间的关系在这个队列.
主要方法:
- 使用FreeSurfer和Coon Toolbox进行分析的MRI扫描 (T1加权,静止状态fMRI).
- 社会情绪评估包括对社会认知,道德判断,延迟折扣和情绪调节的测试.
- 33名低风险早产 (30-36周GA) 和29名满期 (37-42周GA) 年轻成年人 (20-32岁) 的比较.
主要成果:
- 在早产和长产组之间,社会情绪结果或杏仁体体积没有显著差异.
- 低风险的早产的年轻人表现出左桃体和右桃体之间增加的FC以及集群层面的中间前皮层 (MedFC).
- 杏仁体和MedFC之间增加的FC与早产组中更好的社会情感结果相关.
结论:
- 低风险的早产不会影响年轻成人社会情感结果或杏仁体体积.
- 尽管没有结构上的差异,但在低风险的早产年轻人中存在改变的杏仁体 - 中介前皮层功能连接.
- 这种增强的连接性可能是一种与社会情感功能相关的补偿机制.
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