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澳大利亚原住民和托雷斯海峡岛民的自身免疫性风湿性疾病:我们知道什么?
Laura E Eades1, Jason Sines2, Alberta Y Hoi1
1Centre for Inflammatory Diseases, Monash University, Clayton, Victoria 3168, Australia; Rheumatology Department, Monash Health, Clayton, Victoria 3168, Australia.
Seminars in arthritis and rheumatism
|January 18, 2024
概括
本综述研究了土著和托雷斯海峡岛民的自身免疫性风湿性疾病 (AIRD),突出了超出系统性红斑狼 (SLE) 的知识差距,以改善健康结果.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 自身免疫性类风湿性疾病 (AIRD) 包含多系统性炎症状况,如结缔组织疾病,慢性炎症性关节炎,沙尔科毒症和全身性血管炎.
- AIRD可导致显著的发病率,降低生活质量和增加死亡率,系统性红斑狼 (SLE) 在澳大利亚原住民和托雷斯海峡岛民中特别严重.
- 了解澳大利亚各地的AIRD患病率和变异对于优化所有人口的管理至关重要.
研究的目的:
- 审查有关AIRD (不包括SLE) 在土著和托雷斯海峡岛民中的当前知识.
- 为了确定这些人群的流行率,表型和疾病结局数据.
- 突出这些社区对AIRD的研究和理解现有的差距.
主要方法:
- 在原住民和托雷斯海峡岛民中对AIRD (不包括SLE) 的现有研究进行文献综述.
- 综合有关患病率,临床表现 (表型) 和疾病结果的数据.
- 确定研究缺口和需要进一步研究的领域.
主要成果:
- 在土著和托雷斯海峡岛民中报告了除SLE以外的AIRD有限的记录病例.
- 在了解这些人群中各种AIRD的流行率,特定表型和长期结果方面存在重大差距.
- 现有数据表明潜在的诊断不足和独特的疾病表现.
结论:
- 在土著和托雷斯海峡岛民中,有必要对AIRD (不包括SLE) 进行更多研究.
- 解决知识差距对于制定文化上适当和有效的医疗保健策略至关重要.
- 改善数据收集和研究对于减少AIRD管理中的健康差异至关重要.
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