18F-FDG PET/CT在CT导向肺活检中的解剖和代谢指导
Konstantinos Stefanidis1, Ioannis Bellos2, Elissavet Konstantelou3
1Radiology Department, King's College Hospital NHS Foundation Trust, London, UK.
European journal of radiology
|January 18, 2024
概括
-18脱氧葡萄糖 (18F-FDG) 皮肤针肺活检 (PNB) 之前的PET/CT成像显著提高了诊断准确性和安全性. 活检前PET/CT增强了向,减少了并发症,并增加了成功率,特别是在肺部质量方面.
科学领域:
- 核医学成像技术 核医学成像技术
- 干预性放射学是干预性的放射学.
- 肺部诊断 肺部诊断 肺部诊断
背景情况:
- 通过CT指导的皮肤针肺活检 (PNB) 对于诊断肺病变至关重要.
- 优化PNB准确性,产量和安全性仍然是一个持续的临床挑战.
- 来自PET/CT的代谢信息可以指导活检的向.
研究的目的:
- 评估18F-FDG PET/CT作为CT引导PNB的代谢指南的作用.
- 评估PET/CT对PNB诊断准确度,产量和安全性的影响.
- 为了确定皮质检前PET/CT是否会改善PNB的表现,与皮质检后或没有PET/CT相比.
主要方法:
- 在3年内对340名患有可疑肺病变的患者进行PNB后期分析.
- 患者被分为三个组:PNB前PET/CT,PNB后PET/CT和没有PET/CT.
- 活检结果与组织病理学的相关性,重点关注PET/CT最大活性区域 (MAA).
主要成果:
- 总体诊断率为83.9% (95.8%是恶性).
- 活检成功率明显高于PNB前PET/CT (88.8%) 与没有PET/CT (78.9%) 相比.
- 向PET/CT-MAA改善了成功率 (88.8%与52.8%相比),减少了针刺 (2.6与3.1相比),并减少了并发症 (4.5%与10.9%相比),特别是在群体中.
结论:
- 预活检18F-FDG PET/CT为CT引导的PNB提供了有价值的代谢指导.
- 定位到PET/CT最大活性区域显著增加了诊断产量和活检成功率.
- 活检前PET/CT改善PNB性能,减少并发症,对肺部质量特别有益.
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