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Updated: Jul 5, 2025

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通过激活BMP4信号传递,AEBP1促进了乳头甲状腺癌的进展

Gaoda Ju1, Tao Xing2, Miaomiao Xu3

  • 1Department of Medical Oncology, Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China; Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Sciences & PUMC, Beijing 100730, China; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China.

Neoplasia (New York, N.Y.)
|January 18, 2024
PubMed
概括

脂肪细胞增强剂结合蛋白1 (AEBP1) 通过促进上皮-甲状腺介质过渡 (EMT) 来驱动乳头甲状腺癌 (PTC) 的进展和转移. 针对AEBP1-骨形态遗传蛋白4 (BMP4) 轴为先进的PTC提供了一个潜在的治疗策略.

关键词:
脂肪细胞增强剂结合蛋白1 (AEBP1) 是一种骨形态遗传蛋白4 (BMP4) 信号传递皮质 - 介质细胞过渡.乳头甲状腺癌是一种乳头甲状腺癌.

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