通过从药用植物中提取的活性代谢物减轻 sciatica 损伤引起的神经病痛
Abdul Nasir1, Ome Kalsoom Afridi2, Sami Ullah3
1Department of Anesthesiology, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Medical Research Center, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Pharmacological research
|January 18, 2024
概括
药用植物为 sciatica,一种常见的神经疾病提供了有希望的自然治疗方法. 本综述确定了来自各种植物家族的强效植物化学物质,可以缓解与坐骨髓炎相关的神经病痛.
科学领域:
- 药理学 药理学是指药理学的学科.
- 民族植物学 民族植物学
- 神经学 神经学
背景情况:
- 坐骨神经痛,一个普遍的全球背部疾病,涉及坐骨神经刺激,炎症和压缩.
- 目前的 sciatica 治疗方法正在从药物转向来自药用植物的植物化学物质.
- 需要新型的植物化学物质,具有抗神经病的潜力,用于治疗 sciatica.
研究的目的:
- 确定各种药用植物中的强效植物化学物质,以缓解 sciatica 中的神经病痛.
- 审查 sciatic神经疼痛的病理生理学和细胞机制.
- 探索植物和植物化学物质的药理潜力,使用坐骨神经损伤的动物模型.
主要方法:
- 在主要的科学数据库 (Medline,PubMed,Web of Science,Scopus,ScienceDirect,Google Scholar) 进行了广泛的文献搜索.
- 对基于动物模型的坐骨神经损伤引起的疼痛进行了审查研究.
- 分析了已识别的植物化学成分及其治疗应用.
主要成果:
- 确定了39个植物家族,包括Lamiaceae,Asteraceae,Fabaceae,Apocyanaceae和Cucurbitaceae,具有有效的治疗 sciatic神经损伤引起的疼痛.
- 植物化学分析显示,黄类 (53%),类和类 (15%),类 (13%),和糖类 (6%) 是神经病痛治疗的关键成分.
- 药用植物在治疗坐骨神经受伤引起的疼痛方面具有显著的潜力.
结论:
- 来自药用植物的植物化学物质代表了急性和慢性 sciatic损伤诱导的神经病痛的可行的治疗点.
- 这篇综述强调了天然化合物的有效性,用于治疗坐骨髓炎.
- 对植物衍生化合物的进一步研究可能会导致新的坐骨髓炎疗法.
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