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对HIV-1 Vif多态性选择压力的全球和时间动态的计算探索

Md Sakil Arman1, Md Zafrul Hasan1

  • 1Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet 3114, Bangladesh.

Virus research
|January 18, 2024
PubMed
概括

艾滋病毒-1 Vif 蛋白通过保护关键功能区域,特别是与 APOBEC3 相互作用的区域,适应宿主防御. 这种由免疫压力驱动的适应性表明,特定的Vif区域是HIV-1感染的潜在治疗点.

关键词:
在 APOBEC3 中,APOBEC3 是Entropy Entropy进化趋势的演变趋势艾滋病毒-1 Vif有HLA限制的CD8+T细胞.免疫系统的压力.突变的动态 突变的动态突变性可塑性 突变性可塑性蛋白质的稳定性 蛋白质的稳定性dn/ds dn/ds 在线播放

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