慢性抗凝药与术后并发症的风险增加有关,在无菌修复后,全关节整形术
Kevin Y Heo1, Rahul K Goel2, Andrew Fuqua1
1Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia.
The Journal of arthroplasty
|January 18, 2024
概括
慢性抗凝药 (AC) 治疗的患者在修复整部关节整形术 (rTHA) 后面临更高的并发症风险. 这包括感染率增加和机械问题,需要仔细的患者咨询.
科学领域:
- 整形外科手术 整形外科手术
- 关节质整术是指关节质整术.
- 患者安全 患者安全
背景情况:
- 由于人口老龄化,修订关节整形术 (rTHA) 的数量正在增加.
- 慢性抗凝血 (AC) 与初级THA的并发症有关,但其对rTHA的影响不太清楚.
研究的目的:
- 为了比较慢性AC和非AC患者在无菌rTHA中的术后并发症率.
主要方法:
- 对接受无菌rTHA (2014-2019) 的9421名患者的回顾性分析.
- 两个队列:慢性AC (n=1,790) 和没有慢性AC (n=7,631).
- 90天和2年的并发症的比较,控制共变量.
主要成果:
- 慢性AC患者患90天假肢关节感染 (PJI) (OR 3.2),手术部位感染 (OR 3.6) 和机械并发症 (OR 3.5) 的几率更高.
- 在2年后,慢性AC患者的PJI (OR 3.3) 和机械并发症 (OR 3.2) 的几率增加.
- 慢性AC患者在2年内重新手术的几率更高 (OR1.9).
结论:
- 在无菌rTHA后,慢性AC患者经历了显著更高的90天和2年的并发症率.
- 增加的风险包括PJI,手术部位感染和机械假肢问题.
- 对接受rTHA的AC患者来说,关于风险-益处的多学科咨询至关重要.
相关概念视频
Anticoagulant Drugs: Low-Molecular-Weight Heparins
701
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
701
Disorders of Hemostasis
918
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
918


