慢性压力作为质瘤发展和进展的新兴风险因素
Lan Yi1, Xiang Lin1,2,3, Xiaoling She2
1Institute of Cytology and Genetics, The Hengyang Key Laboratory of Cellular Stress Biology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
慢性压力显著影响质瘤,这是一个常见的脑瘤,预后不好. 本综述提出了压力系统的新模型,以澄清其复杂的作用,并探索治疗策略.
科学领域:
- 神经瘤学神经瘤学
- 压力生理学 压力生理学
- 分子生物学分子生物学
背景情况:
- 质瘤是原发性恶性脑瘤,预后不佳.
- 质瘤患者经历了显著的心理压力,包括焦虑和恐惧.
- 由于复杂的机制和个体变异性,慢性压力 (CS) 在质瘤进展中的确切作用尚不清楚.
结论:
- 拟议的压力系统模型为CS对质瘤的影响提供了新的视角.
- 对分子机制的进一步研究可以确定新的治疗点.
- 解决慢性压力的药理干预措施可能会改善质瘤患者的结果.
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