这是一个Echiura Urechis unicinctus的染色体级基因组组合
Yunying Cheng1, Ruanni Chen2, Jinlin Chen2
1Fujian Key Laboratory on Conservation and Sustainable Utilization of Marine Biodiversity, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou, 350108, China. 2680@mju.edu.cn.
Scientific data
|January 18, 2024
概括
这项研究为Urechis unicinctus,一种具有营养价值的海洋虫提供了高质量的染色体级基因组组. 这种基因组资源有助于理解它的进化,并促进分子繁殖的努力.
科学领域:
- 海洋生物学 海洋生物学
- 基因组学就是基因组学.
- 分子进化分子进化
背景情况:
- 埃奇乌拉 (Echiura) 是一种海洋虫家族,它需要强有力的遗传学证据来准确地确定遗传学位置.
- 乌雷奇斯 (Urechis unicinctus) 是一个Echiuran物种,以其营养,药用特性和在潮区的弹性而闻名.
研究的目的:
- 为了生成Urechis unicinctus的高质量的染色体级基因组组.
- 为基因组学分析,基因组进化研究和U. unicinctus.分子育种提供基础资源.
主要方法:
- 结合了PacBio长读,Illumina短读和Hi-C测序技术.
- 进行了基因组组装,对重复序列的注释,蛋白质编码基因和非编码RNA (miRNA,tRNA,rRNA,snRNA).
- 通过BUSCO分析评估基因组的完整性.
主要成果:
- 为U. unicinctus生成了约1,138.6 Mb的染色体级基因组组,其中97.82%的基因被定在17个伪染色体中.
- 标注揭示了482.1 Mb的重复序列,21,524个蛋白质编码基因和各种非编码RNA.
- 基因组组和基因预测完整性分别得到了93.5%和91.5%的验证.
结论:
- 这项研究显著提高了U. unicinctus基因组组装的质量.
- 这种基因组资源对于未来的Echiuran基因组进化和分子生物学研究至关重要.
- 该组件为分子育种提供了基础,并更深入地了解了U. unicinctus的适应性.
相关概念视频
Lampbrush Chromosomes
7.9K
In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
7.9K
Genome Annotation and Assembly
18.9K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.9K
Evolutionary Relationships through Genome Comparisons
5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K


