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Updated: Jul 5, 2025

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使用GECKO工具箱3.0重建,模拟和分析受酶约束的代谢模型

Yu Chen1,2, Johan Gustafsson1, Albert Tafur Rangel1,3

  • 1Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.

Nature protocols
|January 18, 2024
PubMed
概括

GECKO 3.0通过结合酶制约因素来增强基因组规模的代谢模型 (GEMs),改善了细胞代谢的预测. 这种方法可以创建受酶约束的代谢模型 (ecModels),在各种生物体中表现更好.

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