简化的算法和集成的HCV护理模型是否能改善注射药物使用者与护理,保留和治愈的联系? 一个务实的质量改进随机控制试验协议
Stacey L Klaman1, Job G Godino2, Adam Northrup1
1Laura Rodriguez Research Institute - Family Health Centers of San Diego, 1750 Fifth Avenue, San Deigo, CA, 92101, USA.
这项研究评估了一家移动诊所的综合护理模式,用于治疗注射药物使用者 (PWID) 肝炎C病毒 (HCV). 创新的"一站式"方法旨在改善治疗的启动和维持,解决HCV护理方面的差异.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 慢性肝炎C病毒 (HCV) 影响了美国数百万人,在圣地亚哥县有显著的流行.
- 注射毒品的人 (PWID) 和那些经历无家可归的人面临HCV的治疗差异.
- 直接作用抗病毒药物 (DAA) 提供高疗效,正在探索简化治疗算法.
研究的目的:
- 评估街头"一站式诊所"移动诊所模型对HCV治疗的有效性.
- 为了比较一个集成的移动诊所和常规护理之间的HCV治疗启动和保留率.
- 解决PWID和无家可归人口中对HCV的接入和治疗障碍.
主要方法:
- 一个准实验性的,前性的,比较的疗效试验.
- 大约有200名慢性HCV注射药物患者被分配到"简化护理"途径或"常规护理"途径中.
- 区块随机化与1:1的比例被用于组分配.
主要成果:
- 这项研究旨在比较干预组和对照组之间的HCV治疗启动率和保留率.
- 通过将在与注射器服务计划 (SSP) 相邻的移动诊所接受护理的患者与通过社区诊所接受通常护理的患者进行比较来评估结果.
结论:
- 之前的研究支持在移动诊所进行HCV治疗的简化算法和临床检测.
- 这项研究探讨了创新,综合护理系统对HCV治疗启动和PWID级联结果的影响.
- 通过移动健康解决方案,有机会改善对弱势群体的HCV护理.
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