从2000年到2022年,对病毒感染中的m6A甲基化进行了参考资料分析
Xing Tao1,2, Gang Wang1,2, Wudi Wei1,2,3
1Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Virology journal
|January 18, 2024
概括
病毒感染中的N6-甲基氨酸 (m6A) 甲基化是一个不断增长的研究领域. 图书统计分析揭示了关键趋势和未来的热点,如METTL3及其在癌症进展和干扰素反应中的作用.
科学领域:
- 分子生物学分子生物学
- 病毒学 病毒学
- 生物信息学是一种生物信息学.
背景情况:
- N6-甲基氨酸 (m6A) 甲基化是一种重要的转录后修饰,在病毒感染中具有新兴意义.
- 尽管m6A甲基化越来越重要,但在病毒感染研究中对m6A甲基化的文献分析很少.
- 这项研究解决了对该领域研究动态的全面概述的需求.
研究的目的:
- 在病毒感染中可视化和分析m6A甲基化研究热点和趋势.
- 为当前的研究环境提供客观和全面的概述.
- 确定未来研究方向的新兴和下降的主题.
主要方法:
- 从科学网络核心收藏中对2000年至2022年的出版物进行图书法分析.
- 数据选和检索,结果有319个合格记录.
- 使用CiteSpace和Bibliometrix软件包进行可视化和分析.
主要成果:
- 出版物来自28个国家,其中中国和美国是主要贡献者.
- 关键的研究术语包括m6A,COVID-19,表体转录学,METTL3,乙型肝炎病毒,先天免疫和HIV-1.
- 主题映射表明METTL3,植物病毒,癌症进展和I型干扰素 (IFN-I) 是当前和未来的研究热点.
结论:
- 病毒感染中的m6A甲基化代表了不断扩大和重要的科学研究领域.
- METTL3,植物病毒,癌症进展和IFN-I被确定为潜在的未来研究热点.
- 这些发现提供了对这个研究领域中不断变化的趋势和重点领域的洞察.
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