相关实验视频

Updated: Aug 11, 2026

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures
11:22

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures

Published on: December 22, 2014

人类视网膜母细胞瘤敏感性基因:克隆,鉴定和序列

W H Lee, R Bookstein, F Hong

    Science (New York, N.Y.)
    |March 13, 1987
    PubMed
    概括

    研究人员确定了13q14染色体上的视网膜母细胞瘤敏感性 (RB) 基因,这对了解儿童眼癌至关重要. 在视网膜母细胞瘤瘤中观察到异常的RB基因转录和删除,这表明它在癌症发展中的作用.

    更多相关视频

    Reconstruct Human Retinoblastoma In Vitro06:52

    Reconstruct Human Retinoblastoma In Vitro

    Published on: October 11, 2022

    Generation of Retinal Organoids from Healthy and Retinal Disease-Specific Human-Induced Pluripotent Stem Cells09:47

    Generation of Retinal Organoids from Healthy and Retinal Disease-Specific Human-Induced Pluripotent Stem Cells

    Published on: December 9, 2022

    相关概念视频

    Rous Sarcoma Virus (RSV) and Cancer01:03

    Rous Sarcoma Virus (RSV) and Cancer

    Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
    RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
    The Retinoblastoma Gene01:20

    The Retinoblastoma Gene

    Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
    The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...