使用E-vita开放NEO的全门更换和冷大象的一年结果
Chong Hoon Kim1, Tae-Hoon Kim1, Ha Lee2,3
1Department of Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
概括
该E-vita开放NEOTM混合假体显示了有利的1年临床结果,用于冷象 (FET) 修复的全主动脉门置换. 这项研究证实了其在治疗广泛的大动脉病理方面的有效性,其存活率高,并发症率低.
科学领域:
- 心血管外科心血管外科
- 胸前主动脉手术 胸前主动脉手术
- 大动脉动脉瘤和剖析修复修复
背景情况:
- 广泛的大动脉病理需要复杂的手术修复,通常涉及全面的大动脉门置换.
- 冷象 (FET) 技术是管理这些条件的关键组成部分,提供了一个稳定的近邻着陆区.
- 评估像E-vita Open NEOTM这样的新型混合假肢对于改善患者的治疗结果至关重要.
研究的目的:
- 为了评估E-vita Open NEOTM混合假肢在FET的全大动脉门置换中的1年临床结果.
- 为了评估这种假肢在急性大动脉解剖,慢性大动脉解剖和胸前大动脉动脉瘤患者中的安全性和有效性.
- 确定住院死亡率,中风,脊髓损伤和重新手术的比例.
主要方法:
- 一项包括167名患者在内的队列研究,这些患者在2021年4月至2023年3月期间使用E-vita Open NEOTM假肢用FET进行了全额门置换.
- 根据大动脉病理,患者被分为三组:急性大动脉剖析,慢性大动脉剖析和胸大动脉动脉瘤.
- 主要终点是住院死亡率;次要终点包括术后中风,脊髓损伤,为出血重复切骨术以及1年生存率和再干预率.
主要成果:
- 这项研究包括167名患者 (55.1%急性剖析,12.0%慢性剖析,32.9%动脉瘤).
- 观察到低的住院死亡率 (1.8%),中风 (1.8%),脊髓损伤 (1.8%) 和重复脊髓切割 (3.0%),没有显著的群体间差异.
- 一年生存率为95.9%,所有大动脉手术的一年自由率为90.3%,无计划干预率为92.0%.
结论:
- 使用E-vita Open NEOTM混合假肢用FET整体大动脉门置换显示出良好的1年临床结果.
- 假肢似乎安全有效治疗广泛的大动脉病理,包括剖析和动脉瘤.
- 需要进一步的长期跟踪,以充分确定E-vita Open NEOTM假肢的耐用性和长期疗效.
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