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Updated: Jul 5, 2025

CRISPR/Cas9 Gene Editing to Make Conditional Mutants of Human Malaria Parasite P. falciparum
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Published on: September 18, 2018

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假定Plasmodium falciparum氨酸合成酶的抗疟疾目标脆弱性

Nirut Leela1, Parichat Prommana2, Sumalee Kamchonwongpaisan2

  • 1Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Bangkok, Thailand.

PeerJ
|January 19, 2024
PubMed
概括

在Plasmodium falciparum中的甲氨酸合成酶 (MS) 并不是一个可行的抗疟疾点. 基因编辑表明,抑制二叶酸减少酶-胺酸合成酶 (DHFR-TS) 显著损害了寄生虫的生长,与MS抑制不同.

关键词:
在GLMS里波切换器上,GLMS里波切换器GlmS ribozyme 里波酶 的使用情况.疟疾:疟疾是一种疾病.甲氨酸合成酶的使用方法原菌 (Plasmodium falciparum) 是一种有毒的病毒.针对目标漏洞的目标漏洞

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