在COVID-19感染期间使用的血栓预防或抗凝剂后的月经变化
Omnia B Bakr1, Alaa H El-Feky1, Ibrahim A Abdelazim1
1Department of Obstetrics and Gynaecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Przeglad menopauzalny = Menopause review
|January 19, 2024
概括
感染COVID-19可能会导致显著的月经变化,包括改变流量持续时间. 在COVID-19治疗期间使用的血栓预防或抗凝剂进一步加剧了这些月经不规则.
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- COVID-19 感染与各种生理变化有关.
- 受COVID-19影响的妇女中越来越多地报告了月经周期不规则.
- 抗凝血剂等COVID-19治疗对月经健康的影响需要进一步调查.
研究的目的:
- 为了调查COVID-19感染后的月经变化.
- 评估COVID-19期间的血栓预防或抗凝剂使用与月经模式改变之间的关联.
主要方法:
- 一项涉及176名被诊断患有COVID-19的参与者的回顾性研究.
- 通过在线调查问卷收集的数据.
- 使用二次 (χ2) 试验进行统计分析.
主要成果:
- 在COVID-19感染后,与感染前时期相比,月经周期持续时间 (2至<5天和>7天) 显著增加 (p=0.005和p=0.0009).
- 在COVID-19期间使用血栓预防或抗凝剂与大量月经变化有关,包括月经流量增加 (37.8%),持续时间长 (18.5%为2-5天,59.7%为7天),接触出血 (5.9%) 和异常模式 (6.7%).
结论:
- COVID-19 感染与显著的月经不规则有关.
- 在COVID-19治疗期间的血栓预防和抗凝药疗法与月经模式的显著变化相关.
相关概念视频
Anticoagulant Drugs: Low-Molecular-Weight Heparins
701
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
701
Disorders of Hemostasis
918
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
918
Disorders of the Female Reproductive System
364
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
364
The Menstrual Cycle
834
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
834
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
525
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
525
Secretory Phase
740
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
740


