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Updated: Jul 5, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

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石墨烯酸衍生物作为核受体RORγtt的强大的调节剂

Somaya A Abdel-Rahman1,2, Simone Brogi3, Moustafa T Gabr1

  • 1Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine New York NY 10065 USA mog4005@med.cornell.edu.

RSC advances
|January 19, 2024
PubMed
概括

新的3-oxo-lithocholic 酸胺体显示出作为与视网酸受体相关的孤儿受体 γt (RORγt) 调节剂的前景. 这些化合物有效抑制RORγt活性并减少IL-17A的表达,为自身免疫性疾病治疗提供了潜力.

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