术后系统性炎症反应综合征预测,选择性骨切除术后患者的死亡率增加
Liyuan Peng1, Qi Gan2, Yangchun Xiao3
1Department of Critical Care Medicine, Affiliated Hospital of Chengdu University, Chengdu, Sichuan, China.
Frontiers in surgery
|January 19, 2024
概括
切除术后的全身炎症反应综合征 (SIRS) 预测死亡率,特别是当延迟时. 异常白细胞计数是SIRS的主要指标,突出显示了它们对患者结果的重要性.
科学领域:
- 神经外科 神经外科
- 关键护理医学 关键护理医学
- 炎症反应 炎症反应
背景情况:
- 切割患者面临着因过度炎症反应而出现的重大风险.
- 系统性炎症反应综合征 (SIRS) 是一个常见的切术后并发症.
研究的目的:
- 为了评估术后SIRS在骨切割患者的预后价值.
- 为了确定SIRS和骨切割后30天死亡率之间的关联.
主要方法:
- 对12887名骨切割患者的回顾性队列研究 (2011年1月至2021年3月).
- 基于低热/高热,短呼吸,白血症/白细胞症或短心的SIRS诊断.
- 单变量和多变量分析检查了SIRS发育和30天死亡率.
主要成果:
- 超过一半 (52.2%) 患有SIRS;1.22% 经历了30天死亡率.
- SIRS与30天死亡率独立相关 (OR,1.57).
- 延迟的SIRS,而不是早期的SIRS,预测死亡率;升高的白细胞计数是主要贡献者.
结论:
- 手术后的SIRS是骨切割患者30天死亡率的常见和独立预测因素.
- 只有延迟发病时,SIRS的预测值才具有意义.
- 异常的白细胞计数是SIRS在切术后发展的最有影响的因素.
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