Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Nuclear Transmutation03:20

Nuclear Transmutation

17.6K
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
17.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Morita Therapy-Based Nursing Support for Socially Withdrawn Japanese Youth (Hikikomori) with Gaze Phobia: A Case Report.

Reports (MDPI)·2026
Same author

Identifying predictive hematological biomarkers for radiation exposure by machine learning in mouse models.

Communications medicine·2026
Same author

Stable and tunable MeV γ-ray generation via dual-laser inverse Thomson scattering from a laser-plasma accelerator.

Scientific reports·2026
Same author

FLASH reduces radiation-induced oral mucositis in a mouse model of Fanconi anemia.

bioRxiv : the preprint server for biology·2026
Same author

A quantitative proteomics dataset for assessment and prediction of low dose X-ray radiation exposure in mice.

bioRxiv : the preprint server for biology·2026
Same author

Spherical radiomics for radiogenomic assessment of glioblastoma heterogeneity.

Neuro-oncology advances·2026
Same journal

Non-Thermal Plasma Accelerates Astrocyte Regrowth and Neurite Regeneration Following Physical Trauma In Vitro.

Applied sciences (Basel, Switzerland)·2026
Same journal

The Basic Reproduction Number for Petri Net Models: A Next-Generation Matrix Approach.

Applied sciences (Basel, Switzerland)·2026
Same journal

Tetracenomycin Aglycones Primarily Inhibit Cell Growth and Proliferation in Mammalian Cancer Cell Lines.

Applied sciences (Basel, Switzerland)·2026
Same journal

Neuroengineering Frontiers: A Selective Review of Neural Interfaces, Brain-Machine Interactions, and Artificial Intelligence in Neurodegenerative Diseases.

Applied sciences (Basel, Switzerland)·2026
Same journal

Engineering Brain Injury In Vitro: Human iPSC-Based Organoids in Microfluidic Systems.

Applied sciences (Basel, Switzerland)·2026
Same journal

Comparing Virtual Reality and Robotic Training Effects on Balance Ability and Confidence in Older Adults.

Applied sciences (Basel, Switzerland)·2026
查看所有相关文章

相关实验视频

Updated: Jul 5, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.4K

对于FLASH辐射治疗的变革性技术

Reinhard Schulte1, Carol Johnstone2, Salime Boucher3

  • 1Division of Biomedical Engineering Sciences, Loma Linda University, Loma Linda, CA 92350, USA.

Applied sciences (Basel, Switzerland)
|January 19, 2024
PubMed
概括
此摘要是机器生成的。

闪光辐射疗法 (FLASH-RT) 使用超高剂量率来节省正常组织,同时有效地杀死瘤. 这种新的方法为癌症治疗提供了一个新的范式,但技术上的挑战仍然是广泛采用.

关键词:
闪光效应 (FLASH) 是一种闪光效应.粒子加速器中的粒子加速器.辐射治疗疗法 辐射治疗疗法

更多相关视频

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

14.7K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K

相关实验视频

Last Updated: Jul 5, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.4K
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

14.7K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K

科学领域:

  • 医学物理 医学物理
  • 在瘤学瘤学.
  • 辐射生物学 辐射生物学

背景情况:

  • 传统的辐射疗法旨在最大限度地损害瘤,同时通过精确的剂量输送来最大限度地减少正常组织的毒性.
  • 正常组织毒性仍然是当前癌症治疗的重大限制,影响患者的治疗结果和治疗疗效.
  • 放射治疗的治疗指数受到瘤控制和辐射诱导的副作用之间的平衡的限制.

研究的目的:

  • 介绍和探索FLASH辐射疗法 (FLASH-RT) 作为癌症治疗的新模式的潜力.
  • 突出临床前证据支持超高剂量辐射对瘤和正常组织的影响差异.
  • 通过使用新型加速器技术,确定与实施FLASH-RT相关的技术挑战.

主要方法:

  • 采用超高剂量速率进行辐射输送,剂量以几分之一秒的时间 (通常<200毫秒) 输送.
  • 利用临床前研究来研究FLASH-RT对瘤和正常组织的生物学影响.
  • 探索开发能够产生所需超高剂量速率的新型紧型加速器.

主要成果:

  • 实验研究表明,在FLASH-RT条件下,正常组织表现出显著的节约.
  • 在超高剂量速率下,瘤细胞似乎被有效地根除,类似于常规剂量.
  • 一种有利于正常组织保护而不是瘤细胞死亡的差异效应一直被观察到.

结论:

  • FLASH-RT代表了一种有前途的新策略,用于改善放射瘤学中的治疗指数.
  • 在超高剂量率下保存正常组织提供了一个潜在的解决方案,以减少与治疗相关的毒性.
  • 克服加速器设计和剂量输送方面的技术挑战对于FLASH-RT的临床转化至关重要.