心理学辅助治疗试验中的老年人:系统性审查
Lisa Bouchet1,2, Zachary Sager3,4, Antoine Yrondi1,2
1Department of Psychiatry and Medical Psychology, Purpan University Hospital, Toulouse, France.
Journal of psychopharmacology (Oxford, England)
|January 19, 2024
概括
老年人在迷幻药的临床试验中代表性不足,65岁以上的参与者不到1.4%. 然而,现有的数据表明,迷幻药辅助心理治疗是安全的,并且在这个人口群体中被很好地容忍.
科学领域:
- 精神病学是一个精神病学.
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
背景情况:
- 对于心理健康状况的迷幻疗法的临床兴趣正在增长.
- 在老年人中,psilocybin,LSD和MDMA显示出治疗抑郁症,焦虑症和PTSD的潜力.
研究的目的:
- 确定在迷幻药临床试验中老年人的患病率.
- 在这个人群中探索幻觉辅助疗法的安全性和耐受性.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed,EBSCO和EMBASE搜索了用于精神疾病的迷幻物质的英语试验.
- 包括治疗成和存在困境的试验.
主要成果:
- 36项研究符合资格标准,共有1400名参与者.
- 只有19名参与者 (不到1.4%) 的年龄为65岁或以上.
- 没有报告严重的不良事件;轻微的短暂副作用包括焦虑,胃肠道乱和高血压.
结论:
- 有限的数据表明,迷幻药辅助心理治疗对老年人来说是安全的,并且能很好地容忍.
- 进一步严格的调查是必要的,以治疗精神疾病在这个人群.
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