在密码性中风中检测心房动和缺血性中风复发:一个回顾性,多中心的观察性研究
Kenichi Todo1, Shuhei Okazaki1, Ryosuke Doijiri2
1Department of Neurology Osaka University Graduate School of Medicine Osaka Japan.
Journal of the American Heart Association
|January 19, 2024
概括
使用可插入心脏监测器 (ICM) 检测密码性中风后心房动 (AF) 并没有增加中风复发风险. 检测到的AF的抗凝药是常见的,并且在这个患者群体中没有提高风险.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 医疗器械 医疗器械
背景情况:
- 心房动 (AF) 是一个重要的中风风险因素.
- 通过可插入心脏监测器 (ICM) 检测到的密码性中风和AF患者中复发性中风的风险需要进一步调查.
研究的目的:
- 评估密码性中风患者中缺血性中风复发的风险,比较ICM检测到的AF和非AF患者.
主要方法:
- 在8个日本中风中心对370名加密性中风患者进行了回顾性审查,这些患者接受了ICM植入.
- 分析使用考克斯回归模型,具有里程碑和时间依赖分析.
- 在ICM检测到AF的患者和没有患者之间比较中风复发率.
主要成果:
- 在370名患者中,有121人被检测出AF;110人接受了抗凝药.
- 缺血性中风复发的发生率在没有AF的患者中为4.0%,在AF患者中为5.8% (P=0.45).
- 基准和时间依赖分析都没有显示ICM检测到AF的患者复发的风险显著增加.
结论:
- 在ICM检测到的密码性中风和AF患者中,缺血性中风复发风险没有增加,即使随后服用了抗凝药.
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